Hand, Foot, and Mouth Disease: Fast Facts Hand, foot, and mouth disease (HFMD) is a common viral illness of infants and children. The disease causes fever and blister-like eruptions in the mouth and/or a skin rash.
Hand-Foot-and-Mouth Disease (Coxsackie A) in the Child Care Setting Hand-foot-and-mouth disease is a common childhood illness caused by coxsackievirus A16. In many people, infection with the virus causes mild or no symptoms. In others, infection may result in painful blisters in the mouth, on the gums and tongue, on the palms and fingers of the hand, or on the soles of the feet. The fluid in these blisters contains the virus, and symptoms may last for 7 to 10 days. The infection usually goes away without any serious complications.